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Cogent Biosciences

Scientist, DMPK (BioAnalytical and Medical Writing)

Boulder, USAOn-sitePosted 6 days ago

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Job type
Not listed
Work mode
On-site
Level
Not listed
Department
Research and Development (R&D)
Experience
8+ years experience
Posted
Sep 28, 2026

About the role

The Role:

This position works in Drug Discovery to provide bioanalytical support for PK, PK/PD, TK, and TGI experiments across multiple programs. The successful candidate will utilize their strong knowledge of LC-MS/MS bioanalysis to quantitate small molecule drugs in biological matrices (plasma primarily). Independent method development, routine bioanalysis, and communication of high-quality data are hallmarks for the position. Maintenance, troubleshooting, and repair of LC-MS/MS instrumentation and software is expected. Secondary roles of the position include providing technical writing support and review as needed.

Responsibilities:

  • Develop LC-MS/MS methods to quantitate small molecules in biological matrices
  • Routine bioanalysis and data release to DMPK project leads
  • Maintain, troubleshoot, and repair LC-MS/MS instrumentation and software, including coordination with service engineers for complex matters
  • Support technical writing efforts and data QC for preclinical ADME IND efforts
  • Good written and oral communication, including timely electronic laboratory notebook entry
  • Proven work ethic, competence, enthusiasm, independence, and team focus

Qualifications:

  • Minimum of BA/BS with 10 years or MS with 8 years of analytical work in Pharma/Biotech
  • LC-MS/MS
  • Independence, awareness, and multi-tasking in a fast-paced environment
  • Scientific and technical knowledge around small molecule quantitative bioanalysis
  • Strong knowledge of LC-MS/MS instrumentation, troubleshooting, method development, and quantitation
  • Microsoft Office Suite

Preferred Qualifications

  • Sciex QQQ or Shimadzu UPLC
  • Knowledge of DMPK and relationships of in vitro and in vivo assays
  • Non-compartmental PK modeling
  • Report writing
  • Process automation via software, robotics, or liquid handling